Saturday, December 31, 2016

PICTURES & Starting GAPS Diet

Things are going about the same - asthma is still better but not completely better.  Using my nebulizer or inhaler about 3-4 times a day.  Skin is irritated in small areas - neck, arms, and tiny sections of face.  Hives are better since starting the Chinese herbs but again, not completely better.  I have known in my heart for a long time that clean eating is the one step I MUST take in order to fix these issues permanently.  But it can't be haphazard clean eating like I do - 70-80% clean and 20-30% crap.  It's an all or nothing approach in order to turn the tide of my gut and immune system healing.  That has led me to the GAPS diet - the one diet that has shown to reverse autoimmune health problems.  I didn't try GAPS when in TSW - GAPS will cause massive detoxification of the body and since the skin is the main detoxifier, it was not a good idea to aggravate my skin even further.  So now that my skin is strong and has been able to handle me working full time, it is time to attempt GAPS.  I have started a new blog for this journey alone, just like my TSW journey.  I will continue to update things here but not as often.  You can follow me here:

Here are pictures from the last 2 you can see my skin is strong and relatively healthy.  My patches of eczema and irritation seem to stem from my diet as it gets better or worse depending on my dairy and gluten intake.  Hopefully GAPS will fix this issue once and for all.  

As you can see, my forehead and chin both have small patches or irritation as well as my cheek.  They are small and not bothersome.

The other side of my face is about the same.  No obvious swelling or redness.

My neck is probably the worst area - instead of patches, I have lines of irritation.  Very weird.  Other than the area around the lines, no other redness or swelling.  It feels like regular eczema to me and nothing at all like TSW.

My right arm is the worst out of both arms.  But still nothing horrible - just scabs from where I scratch the hives - no red arm/sleeve.  

My hands are dry and have very tiny cracks from the weather I'm guessing.  You can see where I scratched at the dryness of my hand.  

Left hand same as the right.  

And the only area on my legs that is irritated - one small tiny spot.  

Thursday, December 22, 2016

Changes....and more changes....ALL GOOD!

I know it has been a month since I last blogged.  Shame on me!  I had a draft from 2 weeks ago but I deleted it because things have changed dramatically since then.  A few weeks ago my flare was already gone.  But the hives and itching continued after every single meal.  I have tried so many things in regards to my histamine problem.  All anti-histamines do nothing for me.  So I have been at my wit's end given I know there is a "cure" for all of this.  In my opinion I believe it is a system wide approach that begins with healing the gut.  But many of the healing gut foods are also high histamine. It's a vicious circle I've been on the last 2 years.  But I'm getting ahead here.

I'll take it back about 3-4 weeks ago.  My flare was really only lasted maybe 2 weeks. It only stayed on my face, neck, upper chest, and upper arms.  And I can't say it was a full TSW flare.  I didn't have an ounce of ooze anywhere.  It was just really irritable flaky skin that tore easily when I scratched.  I changed up my supplements at that point as I felt everything I was on obviously wasn't doing the whole job.  I added in milk thistle and my go to MSM powder and glutathione.  I still stayed on my active B's, but put everything else to the side.  It seemed to do the trick.  But my asthma was getting worse as well.  It all started with the change in weather.  I broke down and started taking Singulair.  It worked wonders!  Within 2 days I was no longer needing my albuterol.  It was wonderful.  Until a week later.  (At this point all men and children should stop gets personal and very female from here).  So I started spotting which was so odd.  My periods have been like a steady rock for me....always on time with a day here or there thrown off by something minor. Spotting was rare.  So here I am spotting a week before my period was due.  Then no period. I had my tubes tied years ago but took a pregnancy test anyway...completely negative.  So 3 weeks later I started with what I thought was my period.  Except it wasn't normal.  I thought I was going to bleed to death.  It was awful.  A big box of super tampons and bag of super pads gone in 3 days. Something was obviously very wrong.  So I put 2 and 2 together and realized the problems started after beginning the Singulair.  Yep....a rare but serious side effect are nose bleeds and vaginal bleeding. OY!  I stopped the Singulair that day.  In 2 days all bleeding had stopped.  It was obvious to me that Singulair was not going to work for me.  So I called my doctor and asked if I could try the Chromlyn (sp?)'s an old preventative inhaler for asthma that is not a steroid.  Know what mu doc said?  Singulair would not cause bleeding so you need to stay on it and go see an OB/GYN.  Not even joking.  I literally almost lost my shit.

So here I was a few days ago with my asthma getting worse by the day and knowing my doctor was not on my side.  I then remember reading on the FB page about Beth White doing a lot of research on mast cells and so much more (please read up on her findings as they are remarkable!).  She had been reading up on Dr. Li's work out of NYC.  So I did some research as well and read about the Chinese herbs that Dr. Li is having amazing success with regarding asthma and allergies.  I was so amazed at her findings and how much success she is having, that I ordered my own concoction of herbs to help with my asthma and allergies.  Beth just went to NYC to see Dr. Li and I am looking forward to her results.  For me I am only taking 4 herbs that I found would be best to target my specific problems.  I only started them today and already less itching and hardly any need for albuterol.  I'm really excited about this given this is a more natural way to heal the body.  The amazing thing is Dr. Li has discovered that certain herbs will calm the immune system down to the point that some people can now eat things they were once severely allergic to.  Very excited about this!  And she is doing her research at Mt. Sinai so we may end up with some hope for all people with allergies and asthma!

Well, I need to run.  There are more changes to talk about like my new job that I LOVE LOVE LOVE!  I will also have to get some pictures up here soon!  I hope everyone has a wonderful holiday season!

Monday, November 14, 2016

Flaring?? After almost a full year TSW free...

Yeppers....that would be right....I believe I am flaring again after being flare free for well over a year or more.  About a week ago I noticed my face and neck became swollen and red.  Then a few days later the itch started and my skin just sloughed off as if there was no strong bond between the cells.  I have dealt with hives on and off the last 2 years.  I have itched and scratched with nothing more than a few dry patches developing in normal eczema areas.  But my skin never sloughed off - I could scratch to satisfaction and never tear open my skin.  Until this week.  My skin is in shreds and oh the burn!  I forgot just how painful the burning was.

The only good news I have is the flare is localized to my face, neck and a small spot on my upper arms.  It has not spread out and there is not one bit of ooze.  So is it a TSW flare??  Not quite sure.  It seems to have coincided with the weather change perfectly. And my skin has always been worse in spring and fall when mold levels are at their highest.  I do know we have mold in the house we currently live in (rental).  Only time will tell when we finally move out into a brand new home with no mold whatsoever.

For now I will classify this as an isolated flare - not a system wide or a bad flare compared to what I had suffered with in the past.  However it is definitely worse than a normal eczema flare up as it involves my whole face and whole neck.  I continue to take my supplements and have added back in the MSM powder the last 2 days.  Since I added in the MSM, my facial swelling has gone down dramatically.  So I will update more in a week or 2.  I will try to take pictures but my selfie camera on my phone is broken and I can't find my regular camera.

I do know that I can still work which I am thankful for as my hands continue to be flare free and eczema free,  It's a bit uncomfortable at work when things get super busy and I sweat a bit - then it burns more but not to the point I can't deal with it.  Also I still come home and hit the shower.  My neck burns slightly more in the shower, but surprisingly not as bad as I remember showers being during my TSW days.  It's more like the first 2 seconds are "oooh that stings", then it's over.  So again, not sure what this is - whether TSW related or just plain bad eczema/

Tuesday, October 4, 2016

Long term effect of TSW

The one long term effect of TSW that many do not think too much about is the effect long term stagnation has on the body.   I spent a solid 8 months on the couch or in bed.  My husband did most of the errands.  I did go out maybe once a month if that. I remember after I started feeling better around the 9 month mark, I wanted to start exercising. I remember going for a walk outside and barely making it half a mile.  Fast forward 2 years and my TSW is long gone but I am still very weak.  I work 36 hours a week as an ER nurse and that just about kills me.  For the last year I have felt that I could do no more, but dying to get back into shape.   I tried so many times but what would happen is I would have a few good days and then go Gung ho thinking I was ready to get back into shape.  Each time I would overdue it and then feel even weaker.  But I found I was over doing things in all aspects of my life....always trying to do too much because I felt my energy would only last a small amount of time and I NEEDED to get as much done with that energy as possible.  I finally decided about 6 months ago that I needed to slow down and start off very slowly in all things. I set a schedule for myself per se and have stuck to it for the most part.

This month I realized I have accomplished a lot in the last 6 months by going slowly.  I got my kids situated with all their schooling.  I home school them and it gets tough when I work full time but this time I prepared ahead and now we are on a good course.  I got our house in shape and I have started the process of building on our property.  I have all our papers in order and have everything ready to go once we start the closing process.

Now I am back into my healthy eating.  I put our diet on the back burner with so much going on.  But now it's time to focus on that.  So far one week down of clean eating. The kids are on board and there have been no complaints.

And now I come to the exercise thing.  I have been putting this off given how weak I've been. But I know it's time.  So I am canceling my Planet Fitness membership as I've barely used it and I feel that would only hinder me.  You see when I go in I feel like I'm going to be judged for only exercising for 10 minutes. And I end up pushing myself.   But I know I can't push myself.  It's too much for me to do more than I should at this point. My muscles are truly very weak.  So now I am going to walk outside for only 10 to 15 minutes to start.  And today I added in some weight bearing exercises. But only a few where I use big muscle groups.  I do push ups against the wall, squats with no extra weight, and bicep/tricep lifts using cans in my cupboard. It may not seem like a lot but after so many starts and failures from doing too much I figured I stand a better chance of success by going slow.

So for all of you starting to feel better, just give yourself a break if you end up like me where the energy is ever so slow to return. And don't have high hopes that things will go back to "normal" like you were pre TSW.  Some might and many will not.  You have to give your body time to heal everywhere,  not just your skin.  And you may end up having to define a new normal for yourself and your family.  Not trying to be down, but as always,  just keeping it real.

Tuesday, September 6, 2016

On the go and Eczema in all the normal places... sure is busy!  Working full time and even quite a bit of overtime. We are now full blown into the process of building a house from the ground up.  We are no longer going for the simple manufactured home.  We are building the home of our dreams. And that means a lot of time being spent....collecting papers, scanning and emailing said papers, making a ton of phone calls, and going to the property to meet with people for bids and all sorts of matters. While all this is very exciting, it is also very stressful.  With all the new stress, I'm no longer eating as healthy as I should. Eating a ton of carbs, sugars, and even dairy.   And that means eczema!  Not TSW, but regular run of the mill eczema.  Dry itchy skin around the ears, at my elbows,  and now back of my neck. Same places I always got it as a kid.  Every so often I take benadryl for the itching.  And of course the hives are back.... not bad like before as I'm still taking my DAO histamine pills but I seem to get hives from all the stress like when I'm at work.

Overall I'm still doing exceptionally well and no sign of TSW whatsoever.  It seems I need to REALLY focus on healthy eating irregardless of my stress or working conditions. It needs to be a priority. Unfortunately I am booked solid for the next few weeks with short term but important projects on top of work.  Then during the last week of September I will be taking a much needed break. It will be then that I take up focusing back on my health.  Back to healthy eating and exercising more that 2 or 3 times a week.  My goals are to lower my cholesterol (just found out it's 230), lower my resting heart rate (hanging in the 70s and should be 60 or below), get rid of my asthma for good (using inhaler or nebulizer only 10 to 15 % of what I was before), and lose this extra weight on me.  I would love to meet these goals by next Valentines Day.  That will be my 4 year anniversary of TSW.   Wouldn't it be wonderful to be back to what I deem as my old normal self but so much healthier without a sign of eczema, TSW, asthma, or being overweight?  I think this is obtainable even with the stress of working full time AND building a house.

To all the TSW warriors still suffering... keep fighting the good fight. Hang onto hope and never give up trying to find relief. It's worth it in the end. Believe me.

Monday, August 8, 2016

Turning a corner

A little over a week on my new regimen and I have to say that I'm turning a corner in the right direction.  Brain fog is slowly lifting, no hives, less itching,  almost 100% clear skin, and energy to exercise. And I'm eating dairy and gluten. But instead of my skin getting irritated in the typical areas of eczema, all I get is some minor itching.   I've gone to the gym twice in the last few days and am slowly going to get back into shape.  I still get tired easily and seem to need more rest lately but I attribute that to healing given our bodies heal best when at rest.

So the bottom line is for now I'm doing very very good.  Everything is looking up and life is moving along well.  I'm no longer feeling blah or whiny.  I'm working full time and putting in overtime without any consequences to my skin.  And my asthma is fizzling longer carry my rescue inhaler with me everywhere. I might use a puff or 2 a day but that's it.  I've only used my nebulizer once in the last 3 days.  I can't wait to go back to my family doctor for an update and let her know how good I'm doing!  My only physical thing I now need to work on is getting back into shape.  70 lbs to lose or thereabouts.  I won't be weighing myself though except maybe once a month or every other month.  Going to focus on more important numbers like my resting heart rate and BP.  Currently my BP is 127/74 and my resting heart rate is 76.  My goal is to get my HR down to 55 and my BP to 105/65.  I'm turning 44 in a week so I need to keep my heart in good shape.  Many people start blood pressure medicine in their 40s. That's not going to be me if I have anything to say about it!  :)

Praying for all of you still suffering. Keep fighting and keep looking for answers.

Thursday, August 4, 2016

Day 5 of Supplement Protocol

Hmmmm....not sure I wanted to blog since 5 days is not sufficient time to report back on any effectiveness.  But I'm currently in a different "state" and thought I'd just write down some observations and thoughts.

Physically....let's just say I'm not myself.  Within an hour of taking my first dose of the new supplements on Saturday, I felt like my body was purging.  I swear I peed out at least 2 liters in about 2 hours time.  Yet I'm pretty sure I only drank about 300 ml to take all the supplements to begin with and had nothing else to drink that morning.  And let's just say my intestines were well empty within a few hours as well.  No cramps or pain nor any nausea.  So I attributed all the purging to the supplements and not a GI bug.  Every day since I have gone through the same thing after taking the supplements.  Now another thing I noticed is I have been getting car sick going to work and on my way home.  I have developed car sickness with long drives (over 4 hours) in the last 5 years or so. My ride to work is only 45 minutes so not sure why this is happening this week, but it seems related to my supplements. Also I'm feeling more and more fatigued each day.  I know we can go through healing crises as our bodies receive nutrients they are sorely lacking.  Not sure if this is a healing crisis or a bad reaction to the supplements.  I will review in another week.  Writing this down like this not only keeps all my readers up to date on how things are progressing, but it allows me to keep tabs on any and all changes.

Mentally....I thought I was doing OK - but then received a late notice on the electric bill I apparently forgot to have paid by Monday.  Me forget paying a bill???  Never!!  Even during the worst of my TSW, I made sure all bills were paid on time.  It's weird because earlier this week I was filling out the refinancing paperwork for our rental house and thought I was on top of everything because I got all the proper forms in within 2 days.  And then I get the late notice today in the mail and I was truly shocked because it's not like me to miss paying a bill.  Turns out I missed one other bill (the water bill).  So that will be a few days late as well.  I do feel like my brain fog is back but in a different way.  Can't explain it.  I just feel off and sort of mentally tired.

Skin....I know this should be up in the physical department, but with us TSWers, I feel it deserves its own category.  While my skin has been TSW free for about a year, it has still been dry with eczema patches on my arms.  This past week, people at work have commented on how clear my skin is.  And today I woke up feeling like my skin was baby smooth - no dryness!  In fact my eczema spots on my arms are just tiny scabs with no surrounding dryness.  AND I've not followed my diet.  In fact I'm pretty sure I've had dairy almost daily for over a week. (I attribute that to the brain fog and the mental anguish it was causing me to try to stay on a strict diet).  I'm still drinking bone broth daily and eating pretty well - my dairy consists of raw milk from grass fed cows free from antibiotics and hormones. So I am not eating horribly, just not staying away from the foods that normally aggravate my eczema.

Asthma....2 puffs on the inhaler yesterday - 1 puff today.  I am way past due to being able to order more nebs and another inhaler but haven't needed to get those refilled yet.  Still have 1/2 my inhaler left and 1/2 the nebs.  So I would say my asthma is just continuing to get better and better!

Well that's it for now.  It was exhausting writing this....and if I sound whiny, that's because I am.  I feel VERY whiny and that is not like me at all.  So something is going on in my body - going to take a few more weeks I think to get a good idea of whether what is going on is bad or good.  I truly believe it will turn out all good, but feeling this blah feeling is just annoying.  And I just realize I should just stop and apologize - I'm sure many of you suffering horrible TSW right now are like "I wish all I had to worry about is brain fog and fatigue"....and you would be right to feel that way and I apologize!  I like to keep things real here on my blog and me whining over petty symptoms is both insensitive yet real.  There WILL come a point when the same thing happens to you!  And THAT will be a GOOD thing!  

Tuesday, July 26, 2016

Dr. Appointment Summary

I received my summary from my doctor last evening.  It was 19 pages long.  He is very thorough and I am posting his summary for those that want to know what they should be looking for in a specialist in addressing mutations and deficiencies.  I believe in full disclosure and in helping all of you still suffering with TSW.  I never once believed that time was our only healer.  I felt from the beginning that there was a reason some of us went through RSS on steroid creams while others could use the same creams and never once have a problem.  I truly believe the answer lies in our abilities to process chemicals and to heal - or more aptly, the lack of these abilities.  The answer is in our genes.  With the growth of industrialization and chemicals added to our food, water, and air over the last 100 years, our genes have mutated and made many of us more ill than our ancestors.  Some people suffer more in heart disease or lung disease or in our cases, skin disease.  There are ways to bypass some of these genetic mutations and to supplement where our bodies are lacking.  I know many do not believe this and that is your prerogative, but I know too many of those suffering with TSW have found huge relief with this approach (finding out their genetic mutations and deficiencies and addressing them).  I personally spent 30 years slathering on topical steroids of all strengths.  Technically I should still be in TSW at 3.5 years according to some theories.  But I have been TSW free for over a year now - only dealing with hives and regular dry eczema.  Now I am addressing more than just the MTHFR mutation my original naturopathic doctor treated me for.  He did wonders for me, but he was not fully trained in all methylation mutations, hence why my health still has not been 100%.   But now with this new doctor, I can see the BIG light at the end of a now very short tunnel.  And I want to pass on that hope to others.  The issue though at hand is cost.  We have all spent hundreds, if not thousands of dollars searching for relief for our skin.  Seeing a specialist is expensive and often not covered by insurance.  I personally spent $1450 this month alone for 2 appointments and blood work.  I am still waiting to hear from insurance if they will cover the office visits.  But I am not hopeful on this.  The way I look at it is, if I don't improve my hives and asthma, then I will not likely be able to work full time.  But by getting this help and healing, I will be able to not only work full time, but also be functional on my days off for my kids and my household.  I am blessed to have a husband who has worked over time the last 3-4 years so I don't have to worry about working if I'm not able to.  I know not everyone is blessed in these ways.  But seek out help any way you can.  the relief is worth it.

Before I post the report, I want to answer EMJ's question from my last post.  She asked about the special testing for mold my doctor wants to get for me.  Thankfully he included it in his report because I could not remember.  It's called C4a.  And here is a summary of it from


Normal Range:  0-2830 ng/ml
C4a has become the inflammatory marker of greatest significance looking at innate immune responses in those with exposure to Water Damaged Buildings (WDB).   
The complement system is a group of proteins that move freely through your bloodstream.  The proteins work with your immune system and play a role in the development of inflammation.
Each complement activates inflammatory responses, with spillover of effect from the innate immune response to acquired immune response and hematologic parameters.  
These short-lived products are re-manufactured rapidly, such that an initial rise of plasma levels is seen within 12 hours of exposure to biotoxins, and sustained elevation is seen until definitive therapy is initiated.

And here is my report from my doctor (if it doesn't show up properly, I will try to fix it.  For whatever reason it didn't copy well into Blogger so it may take a few hours for me to get it right):

·         Provider: Eric Potter
Date of Service: Thursday 14th of July 2016
Visit Type: Phone Appointment
Assessment and Plan Summary
admin note
Intrinsic (allergic) eczema
Moderate persistent asthma
Deficiency of nutrient element, unspecified
No prescriptions recorded
No orders scheduled
Other Plans
Return_Visit - 2 months
to be set up by Annie
Instructions to Patient - Another copy will be uploaded into your portal under Documents - Handouts.

Below I have prepared a therapy program personalized for your restoration. Your story, your physical findings, your test results, much thought, and much prayer has gone into this program. With this before you, it is time for you and I to begin walking this out. As we talk through this for the first time, there may be some final tweaks. I will make notes and send you a final copy with those minor changes. 
The first section is the summary which just includes my recommendations for supplements, medications, lifestyle, and spirit. We will discuss the second section first, but later when you are looking back to this document, it will be easier to have this summary first. The second section goes into much more detail explaining why we are doing certain things. We will not have time to discuss all of these details so read over this before we meet and have questions in case I don't explain something. You can also look to this second section later to understand why we are doing what we are doing.
Prayer before we start: Father, guide our conversation and use these recommendations to restore health to the one who is suffering. Amen.

*****Summary Recommendations*****
Supplements or Medications which I believe are best for your restoration. 

1) L carnitine 500mg _2__ times per day,
2) Trial of 200 to 250mcg Folinic acid (other form of folate) 
3) Omega 3's goal of 2000 mg daily (EPA+DHA), Work up little by little to that dose. 
4) Alpha Lipoic Acid 100mg twice a day. We will work up to higher doses over time.
5) N acetyl Cysteine 500mg twice a day to help make more glutathione
6) Vitamin E 400 units daily to preserve glutathione.
7) Vitamin D3/k2 Supplement 5000 per day and recheck in 3 months
8) Vitamin C 1000mg per day, if tolerated, increase to 2000mg per day
9) B Minus 1 per day for 2 weeks, (we have in stock) then Start the Hydoxo B12 for 2 weeks, then add folinic acid 200mcg per day. 
10)Seeking Health Phophatidylcholine 1 capsule twice a day.

Neuroprotek which contains quercetin, luteolin, rutin 1 per day and we can determine if need 2 per day. Order from

Follow Up
2 months
to be set up by Annie

Discussed 2 dogs she has at home. May want to consider dog holiday for several days to see if she reacts.

Discussed possibility of Singular. she has prescription from past physician.

Further Testing
1) C4a about $110.
2) Good to check Iron panel for Suberic acid elevation

Dietary Changes:
1. I advise everyone to aim for a low inflammatory diet. The standard American diet increases the degree of inflammation in our bodies. Removing these foods from your diet will improve your health. a) Avoid processed foods. They have less nutrition and more inflammatory additives. b) Avoid Trans-fats as they contribute to cardiovascular decline and ageing. c) Eat a wide variety of colors in veggies and fruits. This increase the anti-oxidants in your diet easily. d) Try to eat mostly organic veggies and fruits to avoid pesticides. Given the expense of organic foods, at least try to avoid the "Dirty Dozen" from the Environmental Working Group's list of the dozen foods with the most pesticides. You can find this on their website or Android/Apple app. e) Try to eat grass fed meat if you eat meat and avoid charring when cooking. f) Avoid using oils for cooking like Canola, sunflower, safflower as they can become trans-fats when heated. Low temp olive oil is okay unless it begins to smoke. Avocado oil can tolerate much higher heat. Use olive or avocado oil for salad dressings.
2) Other dietary:

A) Given asthma symptoms 30-60 minutes after dairy, she mainly avoids.
B) She gets hives and worsened eczema if eat dairy.
C) Given sesame seed anaphylaxis in past, avoid.
D) Given IgE, avoid peanuts, milk. Minimize or avoid Egg and soy and wheat.
E) With any egg intake, take 2 enzymes and avoid under-cooking.
F) Follow smoke point temps to prevent trans fat creation
G) Feel free to add some more olive oil into diet plan.

Lifestyle Recommendations
Exercise: Aim for at least __30__ minutes of exercise _4___ times per week. Exercise means some type of activity which gets your heart rate up slightly and makes your feel a little tired after having done it. This could be walking, cleaning your house quickly, strenuous gardening, jogging, aerobics, pilates, or other things. Ideally it will be something you enjoy or a regular activity that you can adapt to be a form of exercise. If you begin this exercise and feel chest pain/tightness, stop immediately and seek medical attention. If the pain does not stop after stopping the activity, you should probably call 911 for emergency help. During outdoor exercise or exercise that causes sweating, be sure to stay hydrated with water. Also be sure to replace electrolytes lost in sweat like potassium and magnesium. 
Rest: Besides having physical activity to stimulate our metabolism, our bodies require adequate rest. This rest comes in different forms. Daily we need to pace ourselves to prevent excessive fatigue and then get adequate sleep at night. On a weekly basis, we need to monitor how much physical exertion occurs each day and try to minimize high exertional days occurring 2 or 3 in a row. In other words, if you have a high physical stress/exertion day, the next should usually be an easier day. Stacking 2 or 3 or 4 hard days in a row will cause stress hormones to go too high and possibly our immunity to drop, leading to infections. 

A) In New York house, severe mold issue (Severe water damage after hurricane) . In current house, uses air purifiers and cleans well. 

Sleep: Ideally, most people need 7 ½ to 8 ½ hours of sleep per night. There are some genetics which lower the amount and some which lengthen the amount needed. In addition, illness and inflammation in our bodies increases anyone’s need for sleep. During sleep our brains recuperate and establish memory circuits. During sleep our bodies repair tissue damage that occurs during the day. During sleep metabolism slows and we prepare for another day. For you I RECOMMEND: ___7-8_____ Hours per night.
In order to improve sleep quality, there are few practices called sleep hygiene. They are good for everybody even if they don’t solve a problem with insomnia. They include:
1) Exercise during the day primes our bodies to sleep better at night IF we don’t overdo the exertion. Overexertion can cause restlessness and poor sleep.
2) Avoid stimulating activities the last 3 or 4 hours prior to bed. Strenuous exercise or things that cause emotional distress should be limited or avoided altogether.
3) Avoid ‘screen time’ for the last 1 to 2 hours prior to bed. The blue light from TV and computer screens is stimulating to the part of the brain that controls your sleep/wake cycle. This makes it harder to fall asleep after shutting down the screen.
4) You can use computer programs which turn blue light into red hues can help. You can also purchase light bulbs for your bedroom which emit light in the red spectrum more than the blue which is calming. 
5) For the last 30 minutes to 1 hour prior to bed, try to develop a routine with a relaxing activity. This might be reading a calming book or listening to calming music. 
6) If you get to bed and can’t fall asleep, consider getting up from bed and doing a calming activity until you feel sleepy. Regardless, get up the same time as usual the next morning.
7) The bedtime routine should include the fact that you aim for about the same bedtime each night. Aim for an approximate time within 30 minutes either way of your goal. Then awaken approximately the same time each morning. 
8) If you awaken with the need to use the bathroom nightly, try avoiding liquid intake for 2 hours prior to bed. Also, try holding the urge for a few minutes if possible before getting up. Often, the urge will go away and you can fall back asleep. 

Spiritual: We are whole beings, embodied souls if you want to be technical. Attempts to separate body from soul during our earthly experience are full of problems. As we move forward with your care, we hope to see healing and restoration not only physically, but emotionally and spiritually as well. As a Christian, I believe healing spiritually requires following God’s way. What I mean is not a religious to do (or “don’t do”) list. These are activities through which God works. First, I encourage patients to read their Bibles daily. Between the hectic pace of our day and the mental fog of chronic illness, this can be difficult. I just point patients towards the Psalms, a place where I and my family have found much benefit during our trials. Reading one a day is simple and can be very rewarding. Second, I encourage patients to pray over their health. Many of you have likely already done so, but prayer is a persisting activity, so don’t give up. Also, involve others like family members and friends. God wants us to pray for our needs and the needs of each other. Third, look for areas of bitterness, unforgiveness, or broken relationships in your life. These may not be at the heart of your illness, but they can be contributors to it. Work through those issues with a trusted counselor as soon as you can. 
If you have questions about the spiritual aspect of your life, please ask me and we can talk more.

**********23 and Me Report Details *********
COMT 62 , 158 
IgA and IgE

***Important SNPs likely affecting your health:***

DAO General Explanation
You have _1___ significant SNPs for this enzyme.
DAO stands for D Amine Oxidase, an enzyme which metabolizes amine groups in certain substances including histamine. It is found in the gut, outside the cells, primarily. In contrast HNMT is an enzyme that breaks down histamine inside cells. SNPs in this enzyme can slow it down and make the effects of histamine last longer and be more severe. DAO effects gut histamine sensitivities whereas HNMT is more related to other histamine effects. 

You have DAO SNPs which may be clincally important making you more sensitive to histamine. This can present as symptoms of seasonal allergies, skin rashes, Gut sensitivities to histamine foods.

I would also recommend Neuroprotek which contains quercetin, luteolin, rutin 1 per day and we can determine if need 2 per day. Order from

You have copies of SNPs in your MTHFR gene.

MTHFR has garnered much media attention in recent days due to the ongoing discoveries of how the methylation cycle is linked to multiple disease processes. MTHFR stands for methylene tetrahydrofolate reductase, an enzyme which converts one form of the vitamin folate into another that is critical for keeping the methylation cycle functioning. The importance of the methylation cycle and its downstream chemical effects are discussed elsewhere. For now, just know that this cycle and especially this enzyme has been linked to depression, anxiety, neural tube defects in babies, cancer, asthma, autism, chronic fatigue syndrome and many other diseases. The cycle's primary goal is to produce SAMe, a chemical used throughout your body's system to affect hundreds of body functions. 
When SNPs occur in this enzyme, they primarily slow the enzyme down, causing less of the methyl-folate to be produced for the methylation cycle. With less methyl-folate, the methyl-B12 that is used cannot be recycled. Ultimately less SAMe is produced and the enzyme processes which needs SAMe slow down. The dysfunction of these enzymes can lead to symptoms and diseases. MTHFR and the methylation cycle deserve an examination in patients with the symptoms listed above, especially when other causes are not found or the diseases are resistant to standard therapy. 
MTHFR 677 is the best known and understood SNP. One copy of the SNP probably decreases the enzyme activity by 30% by most accounts. Two copies (and thus no normal copy) of 677 probably decrease enzyme activity down by 70%. Of note, a person may have combinations of 1298 and 677 SNPs. Research is unclear on the percentage change in enzyme activity when 1298 and 677 are combined, but all agree that the combination decreases activity. 

RECOMMEND B Minus 1 per day for 2 weeks, (we have in stock) then Start the Hydoxo B12 for 2 weeks, then add folinic acid 200mcg per day. 

You have one or more copies of COMT SNPs.
_1__ H62H - (does not change enzyme, but how much it expresses)
_0__ P199P - (lower activity of enzyme)
_1__ V158M - (changes enzyme to work slower)

COMT stands for Catechol O Methyltransferase, an enzyme found in a variety of tissues of the body. Depending on its location, this enzyme may be used to break down dopamine, epinephrine (adrenaline), and norepinephrine (all are neurotransmitters or chemical signals) in the nervous system. It is also used to break down estrogen in the body. It also breaks down some catechols from our diet. 
The effects of this enzyme may be seen in several diseases. Dopamine plays a role in schizophrenia, ADD/ADHD, and Parkinson's Disease. Norepinephrine imbalance appears to play a role in ADD/ADHD. Breast and ovarian cancers are influenced by estrogen. Depending on the proper functioning of COMT and its relationship to other enzymes, various amounts of different breakdown products of estrogen may increase or decrease cancer and osteoporosis risks. A congenital defect called 22q11 deletion syndrome in which 1 copy of the gene is completely erased places children at increased risk of certain psychiatric disorders.
There are many things which may inhibit this enzyme from breaking down dopamine, norepinephrine, or estrogen. Low levels of SAMe (the methyl donor product of the methylation cycle) or Magnesium will not permit the enzyme to work at full capacity. Many foods contain catechol substances which compete with the primary function and slow it down. Think of more cars trying to drive down a three lane highway and causing a traffic jam. Coffee, tea, quercetin, green coffee extract, sweet potatoes, and other foods will put more stress on the COMT pathway, causing build ups in dopamine, norepinephrine, and estrogen. 
For individuals with SNPs in the COMT enzyme, the enzyme slows down to varying degrees. Basically, the three lane highway narrow to 2 ½ or less lanes. If the traffic of neurotransmitters stay light, the person may function quite normally. If more cars are added to the road by diet or lanes are closed due to lack of SAMe or Magnesium, neurotransmitters levels may increase leading to a variety of emotional or physical symptoms. 
Therapy for COMT SNPs: As always, we never treat SNPs, we treat patients and their root causes to relieve symptoms, restoring proper functioning. If individuals present with anxiety, depression, estrogen dominance, schizophrenia, ADD/ADHD, Autism, Biopolar, Chronic Fatigue, or a few other disease processes AND they have COMT SNPs, then certain dietary changes should be considered as well as supplements addressed. One complicating factor is that COMT is not the only factor in dopamine and norepinephrine levels. VDR, the Vitamin D Receptor, and its SNPs interacts with COMT SNPs. For a full explanation read the VDR notes, but here just know that VDR plays a role in dopamine levels (and thus norepinephrine levels since it is made from dopamine by another enzyme). VDR Taq SNPs cause less dopamine to be made. Since the actual level of dopamine depends on both production and destruction, VDR and COMT must be considered together. 
Beyond the VDR SNPs, other SNPs may play a role in the breakdown and balance of such neurotransmitters. MAO A and MAO B, along with SULT enzymes affect levels of these neurotransmitters as well as serotonin. I will make specific recommendations based on the combination of your SNPs. 

I RECOMMEND Hydroxo B12 2000mg per day.

You have _2__ copies of SNPs out of a possible __4__in NOS2.

NOS2 stands for the inducible nitric oxide synthase 2 enzyme which is found in the liver and is induced (triggered) by various cytokines (cell to cell chemical signals by immune cystem) and lipopolysaccharides to produce nitric oxide. Nitric oxide is a free radical used by the body in several beneficial functions. In the immune system is has tumor killing, viral killing, fungus killing, and bacteria killing actions. Tetrahydrobiopterin (BH4), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and NADPH co-factors are required for catalytic activity. Studies are ongoing which link NOS2 upregulation and down-regulation with various disease states (including autoimmune diseases, infection susceptibility, cancer, asthma, and more).
Dysfunction may place one at risk of higher infection rates if down-regulated (slowed down) or autoimmune disease if up-regulated (sped up). Evidence is not yet clear on the effect of these SNPs.

Adequate cofactors are needed for proper functioning of this enzyme. FAD and FMN from riboflavin are important as well as NADPH produced by the energy cycle. Your specific disease state will determine the treatment. Conditions of high oxidative stress indicate a need for antioxidants and treatment of the oxidative stress root cause (infections, food sensitivities). Chronic infections due to poor functioning of NOS2 indicate a need for immune stimulating therapies. The ultimate goal is to restore balance as this enzyme has an important role in proper body functioning. Too much or too little can each cause problems. 

PEMT General 

You have _1__ SNPs in this gene.

Phosphatidylethanolamine N-methyltransferase. PEMT is a transferase enzyme that catalyzes the conversion of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) in the liver. PEMT uses methyl groups from SAM to make PC; this accounts for about 30% of PC synthesis. PC accounts for more than half of cell wall phospholipid content, and is a crucial component for supporting cell membrane integrity. Supplementing with PC spares valuable methyl groups for use elsewhere. The body can also turn PC in choline for liver support. Adequate choline intake is important.

I RECOMMEND: Seeking Health Phophatidylcholine 1 capsule twice a day. Cost from Seeking Health that I can provide is $17.50 plus $1.62 tax for total $19.12. This provides 100 softgels. You will likely take this twice a day for 2 months, then drop down to once daily maintenance.

Multiple SNPS in IgE and IgA which are forms of antibodies. These genetics may explain why problems have developed with allergies.

**********Possibly important SNPs **********
You have one or more FUT2 SNP variants.

FUT2 stands for fucosyltransferase, an enzyme involve in producing H antigen. Some research points to difficult retaining Vitamin B12 and thus requiring more in the diet or by supplementation. Not clear how important this is at this time. Other studies look at the effect of this enzyme on gut health. SNPs seem to reduce the variety of bacteria in the gut. Homozygous vegetarians may have very low B12 levels. Would consider higher doses of either methyl-B12 or hydoxy-B12 depending on your other SNPs. You should also take a probiotic daily if you are having trouble absorbing B12 or if you have gut problems. 

You have _2__ out of a possible _4__ SNP copies on this report. 

SOD2 stands for Superoxide Dismutase 2. This family of enzyme help protect the body by processing superoxide radicals which if left alone can cause oxidative damage to cells. SOD2 is in our mitochondria where energy production occurs in the cells. The SNPs causes decreased gene function. Chronic alcohol ingestion by persons with two copies causes brain shrinkage at greater rates than those without the SNPs. Chronic oxidative stress can lead to cancer, heart disease, and other chronic illnesses. It also interferes with proper functioning of your methylation cycle. 

You have _2_ out of a possible _4__ SNP copies on this report. 

SOD3 stands for Superoxide Dismutase 3. This family of enzyme help protect the body by processing superoxide radicals which if left alone can cause oxidative damage to cells. SOD3 is found outside our cells to process superoxide free radicals. The SNPs causes decreased gene function. Chronic alcohol ingestion by persons with two copies causes brain shrinkage at greater rates than those without the SNPs. Chronic oxidative stress can lead to cancer, heart disease, and other chronic illnesses. It also interferes with proper functioning of your methylation cycle.

Treat both with Vitamin E (already doing that) and Manganese, but manganese is already high, so don't want to more.

Other SNPs unlikely affecting you, but good to be aware of:
You have SNPs in the CYP2d6 enzyme.

CYP2D6 stands for a cytochrome p450 enzyme which your body uses to detoxify (change so that it can be removed) various chemicals in your body including many drugs (beta-blockers for high blood pressure, rhythm drug for the heart, anti-depressants, the cough medicine dextromethorphan (DM), codeine, diltiazem, nortriptyline, and others. It also helps produce steroids in hormones in the body under normal circumstances. Some SNPs can greatly decrease the ability of the enzyme to function leading to higher levels of these medications in the body.

Therapy is mainly to avoid the medications processed by this enzyme if you know that you have it.

You have a SNP in CYP1B1. This detoxification pathway is involved in steroid metabolism. Having the SNP appears to slightly lower the risk of endometrial cancer. Other cancers are being studied but are not entirely clear yet. 

You have SNPs in this enzyme.
__1__ rs1057910
__1__ rs1799853

This enzyme is one of a large number of enzymes used in the body to break down (metabolize) both chemicals made by the body and chemicals from the environment. They catalyze (facilitate) many chemical reactions in drug metabolism and production of cholesterol,steroids, and lipids. This particular enzyme can be sped up by the antibiotic rifampin. The enzyme breaks down drugs such as phenytoin (Dilantin), tolbutamide (diabetes), ibuprofen (OTC pain medication), and warfarin.

Those with the rs1057910 SNPs may have difficulty breaking down Celebrex, tolbutaminde, phenytoin, glipizide (diabetes), and warfarin (coumadin, blood thinner). These individuals have increase risk of skin reactions to phenytoin and increased risk of bleeding with warfarin (Coumadin). 
Those with rs1799853 SNPs may have difficulty with sensitivity to phenytoin and warfarin. They may also have increased risk of GI bleeding when taking ibuprofen or other NSAIDS. 

Before taking any of these medications, you should inform your doctor of your genetics and discuss how to adjust your dose or choose another alternative.

***********Other Testing Results:***********
Genova Nutreval Report

The following information walks through your Genova report one section at a time. It begins with a short summary of the important highlights of your testing. Specific therapy recommendations are place in the summary for the program report on the first page. Next each section is addressed.

********** Section by Section ********

******** Malabsorption and Dysbiosis ********

Malabsorption Markers
Your phenylacetic acid (PAA) is ___barely___ elevated. This may be from low stomach acid or enzyme activity as well as problems with intestinal motility. Bacterial Dysbiosis is also a possibility. I recommend *********

Bacterial Dysbiosis Markers
DHPPA is ___barely____ elevated, indicating possible Clostridia or Pseudomonas in gut. I RECOMMEND:***** At some point a stool analysis may be needed.
3HPAA is ____mildly____ elevated. This may be due to quercetin intake, increased teas/fruits/grape seed extract (flavanoids) or colonic bacteria. I RECOMMEND: *******
Your Benzoic Acid is __moderately_____ elevated. This may reflect high intake of food such as strawberries with this substance, gut dysbiosis, or high intake of polyphenols such as quercetin, chlorogenic acid, Luteolin, genitstein, or the foods below. Some studies show a possible connection between high benzoic acid levels and slowed cognitive ability.
Foods with polyphenols include blackberries, raspberries, black currants, strawberries, blueberries, kiwi, cherries, plums, apples, pears, chicory, artichoke, coffee, soy, tofu, green tea, apricots, black tea, red wine, and chocolate. 
I RECOMMEND *********

Yeast / Fungal Dysbiosis Markers

******** Cellular Energy and Mitochondrial Metabolites ********

Your Lactic Acid is __mildly____ elevated.
This can occur in a variety of conditions: if sample collected after exercise, low zinc, low oxygen, anemia, lung disease, toxins, low B1, low B6, problems with muscle metabolism.
I RECOMMEND: ___ Zinc ___mg per day, __CHECK level of_ Iron ___ mg per day, ___ Gingko 100mg per day, ___ Detox, ___ B1 ___ mg per day, ___ Vitamin B6 ___mg per day, ___ treat diabetes, _xx__ L carnitine 500mg _2__ times per day, ___ Creatine ___mg per day, ___ magnesium ___mg per day.

Energy Metabolism
Overall good

Fatty Acid Metabolism
You have _____very_____ elevated Suberic Acid. This may be from certain vitamin deficiencies, a very low carb diet, diabetes, or some rare metabolic defects. For you I RECOMMEND: ******** L-Carnitine 500 mg twice day (can be acetyl – L carnitine or L carnitine fumarate). You should also take Vitamin B6 at ***********


******** Neurotransmitter Metabolites ********

******** Vitamin Markers ********

Alpha keto-adipic acid elevation: 
Possible Causes: B3 – niacin deficiency, Pantothenic Acid deficiency, cysteine deficiency, magnesium deficiency, energy deficiency, B1 – thiamin deficiency, B2 – riboflavin deficiency. Toxic metals like arsenic, antimony, mercury, or cadmium. Yeast or fungal infections.

Formimino Glutamic Acid Elevation
You have ___ borderline _______ elevated Formimino Glutamic acid (FIGLU). This can be from low folic acid or severe oxidative stress which interferes with folic acid metabolism. Histidine supplementation can also elevate it in high doses. I RECOMMEND: Methyl-tetrahydrofolate starting 500mcg per day, increasing each week by 500mcg until reach desire dose (To be determined). If you have increased irritability, insomnia, teeth grinding, nightmares, skip a day of this vitamin. *******

IsoValerylGlycine (IVG) elevation
You have ___borderline_____ elevated IVG. IVG is made from another amino acid called leucine. This may be elevated in anorexia nervosa (self starvation) or enzyme defects. It may also be from high leucine intake (__ Yes or _no__ No for you). Symptoms may include weakness. The enzyme defects may respond to treatment with carnitine and glycine or riboflavin. 

I RECOMMEND: ___ alpha lipoic acid, ___ B1/Thiamine, _xxx__ B2/Riboflavin, ___ B3/Niacin, ___ Pantothenic acid, ___ Methyl-folate, xx___ Folinic Acid, ___ B6/pyridoxine, ___ B12 as ___ Methyl-cobalamin - ___ hydroxyl-cobalamin - ___ adenosyl-cobalamin, ___ Cysteine (as n-acetyl cysteine), ___ Magnesium, __xx_ Carnitine, ___ glycine, ___ Ribose .
OR treatment for ___ Heavy metals.

******** Toxin and Detox Markers ********

******** Tyrosine Metabolism ********

******** Essential Amino Acids ********
Across the board, low amino acids – need to increase protein intake- especially tryptophan, taurine, BCAA, methionine

******** Non-essential Amino Acids ********

******** Intermediary Metabolites ********

B Vitamins

Urea Cycle

Glycine and Serine 
High Glycine – should lower supplementation or increase phase 2 detox

Dietary Peptide markers

******** Fatty Acids ********

Omega 3’s
Low – need to add Omega 3 DHA+EPA total 2000 per day for 1 month, then 1000 per day continuing

Omega 9’s

Saturated Fatty Acids

Omega 6’s

Monounsaturated Fats
BUT ………… TRANS FATS high. Need to find sources and remove.

Linoleic / DGLA ratio

Cardiovascular Risk
Not ideal. Increasing Omega 3 and 9’s would help while lowering saturated fats.

******** Oxidative Stress Markers ********
Your glutathione is _____very____ low. If your cysteine is low ____ that needs replacement. Otherwise I RECOMMEND increasing other antioxidants. You are either not making it sufficiently or are using it up too quick. Future possibility is transdermal glutathione as oral form is broken down too rapidly to be useful.

I RECOMMEND: __x_ Alpha Lipoic Acid 200mg twice a day, __x_ Vitamin E, _x__ N acetyl Cysteine (NAC) 600mg twice a day.

Your lipid peroxides are ___barely_______ elevated. This indicates that high oxidative stress has caused damage to your cell membranes. This process is likely ongoing now and needs to be reversed. You need healthy cell membranes for proper functioning of all cell types.

I RECOMMEND: **** : _x__ Alpha Lipoic Acid 200mg twice a day, _x__ Vitamin E, _x__ N acetyl Cysteine (NAC) 600mg twice a day , ___ Selenium ___ , __x__ Vitamin C at _____ mg per day , _____ Oral liposomal glutathione ____mg per day , ____ IV glutathione 

******** Vitamin D *********
Low at 26
- Supplement 5000 per day and recheck in 3 months

******** RBC Elements ********

******** Nutrients ********
Can lower manganese if taking -- not taking, not eating large amounts of nuts.

Others are pretty good

******** Toxins ******** 
Tiny bit of lead
Some Cadmium
- Alpha Lipoic and NAC and Selenium will help detox 
- Can add sweat therapy as well. 

******** Other Testing *********

minimal except sesame 2_
IgE level over 2000

IgE ***********
6 - peanut
4 - cows milk, wheat
3 - soybean, eggwhite
2 - oat
1 - rice

IgG veggies

IgG spices
- Okay

IgE inhalants *****************
Trees -neg
Grasses 4 bermuda, 6 johnson and June

Weeds - Ragweed 5

MOlds 3
Cat 6 cockroach 3 dog 6 Mite 3,2,4

IgE Mold
3 - aspergillus, alternaria,
4 - candida albicans, mucor, rhizopus,
5 -
6 pitryosporum orbiculare

Celiac - gluten
This summary does not show the doctor's notes or specific documentation. If you would like access to additional documentation you must request a copy of your note from your provider
·         Admin Note on 06/27/2016SHOW DETAILS
·         Office Visit on 06/27/2016SHOW DETAILS