OK....came early from work....darn hands were a MESS and there was no way I could work as they just got worse by the hour keeping them bandaged. I can't keep them open to air because of risk of infection but having an occlusive dressing on made them so much worse. Not sure what that means for working next week and so forth but I will worry about it later.
I went to the ND today and was told I have the homozygous type C MTHFR gene mutation. Basically it means my cells can only repair and cleanse at 10-20% of what normal cells do. That's bad. It can cause high homocysteine levels in the blood causing inflammation, heart disease and a ton of other disorders. I wrote a post about this here. Also there is a great blog post by a doctor Jill who explains it way better than I could....http://doccarnahan.blogspot.com/2013/05/mthfr-gene-mutation-whats-big-deal.html
Basically it partly confirms my theory that those of us with TSA/W are part of the 30-40% of the population that has some factor of this MTHFR gene mutation. It would explain why many people do not become addicted to steroid creams at all after years of use (like a cousin of mine), It could also explain the varying ranges of withdrawal symptoms. If I'm right, then people who have severe problems like chronic fatigue, arthritis, and other auto-immune problems and take many years to heal from TSW probably have the worst case scenario for this gene mutation which is homozygous types A and C. And those who seem to have a light case of TSW and heal quickly might just have the heterozygous form of either A or C, but not both. Having the heterozygous form of just one means your cells repair at a rate of 60% compared to normal people's cells.
So why does this only partly confirm my theory? Well we need more people with TSW to be tested. If 100% of people with TSW test positive then we will know the course of treatment can significantly reduce symptoms and possibly length of suffering. With the test results, my ND changed some things. He added a few new things and increased my 5-mthf to 5 mg up from 1 mg. He said while the MSM and glutathione are helpful and needed, the 5-mthf is what I really needed to increase. So he said I can continue with the oral glutathione and stop the IV form as it was not necessary to take the higher IV dose.
If you are interested, just ask your doctor or ND to be tested for the MTHFR gene mutation. It only took a few weeks for my results to come back. I am going to look into trying to get funding together so we can get a bunch of us tested. But if you do get tested, please let me know! I think it would be a very important study to do. And if we have a number of people who got tested and all tested positive, it would give us leverage to get a study going.
That's it for now. I was doing really good this morning but now my hands are a wreck again and typing is making some ooze come out. Hoping it was just the dressings....praying it is gone by tomorrow and I see some healing in them soon!